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- by csisn08 Oct 16, '08Does anyone know why irradiated blood products are a better choice when a patient is immunosuppressed? I was working with a patient received irradiated packed RBCs while undergoing dialysis. Just trying to make sense of the whole thing. Any information would be greatly appreciated.
- Oct 16, '08 by janfrnIrradiation kills most viruses and bacteria that might still be present in the blood. Better to avoid infection than to try and treat it!
- Oct 16, '08 by HappyPediRNDoes your patient also have cancer or a hematological disorder?
- Oct 16, '08 by csisn08He had anemia, with a history of cancer 10 years or so ago. He had a history of DM, kidney transplant, and cirrhosis of the liver. He also had an infection of his fistula site, so janfrn's response makes sense to me. Thank you for your responses.
- Oct 17, '08 by iluvivtIrradiated Blood is primarily used to prevent GVHD (graft vs host disease) and as a secondary benifit destroys the CMV virus. The irradiation prevents lymphcytes from replicating.