Irradiated PRBCs

  1. Does anyone know why irradiated blood products are a better choice when a patient is immunosuppressed? I was working with a patient received irradiated packed RBCs while undergoing dialysis. Just trying to make sense of the whole thing. Any information would be greatly appreciated.
  2. Visit csisn08 profile page

    About csisn08

    Joined: Oct '08; Posts: 5


  3. by   NotReady4PrimeTime
    Irradiation kills most viruses and bacteria that might still be present in the blood. Better to avoid infection than to try and treat it!
  4. by   HappyPediRN
    Does your patient also have cancer or a hematological disorder?
  5. by   csisn08
    He had anemia, with a history of cancer 10 years or so ago. He had a history of DM, kidney transplant, and cirrhosis of the liver. He also had an infection of his fistula site, so janfrn's response makes sense to me. Thank you for your responses.
  6. by   iluvivt
    Irradiated Blood is primarily used to prevent GVHD (graft vs host disease) and as a secondary benifit destroys the CMV virus. The irradiation prevents lymphcytes from replicating.