RSI meds - page 3

out of curiosity... what meds do your docs like to use for RSI. anybody using ketamine, read that it can be useful in hypotensive pt.s and especially with status asthmaticus.... Read More

  1. by   mwbeah
    I agree that lidocaine is a great drug, but may not always be the best choice with cerebral injury.

    Lidocaine preferentially blocks inhibitory pathways centrally and may invoke excitatory phenomena (i.e. seizures) at clinical doses thus increasing CRMO2 which could accentuate apoptosis and cerebral edema. There are several articles from the neuroanesthesia department at Barnes-Jewish in St. Louis that describe this event very well.

    Mike
  2. by   mwbeah
    Quote from mwbeah
    I agree that lidocaine is a great drug, but may not always be the best choice with cerebral injury.

    Lidocaine preferentially blocks inhibitory pathways centrally and may invoke excitatory phenomena (i.e. seizures) at clinical doses thus increasing CRMO2 which could accentuate apoptosis and cerebral edema. There are several articles from the neuroanesthesia department at Barnes-Jewish in St. Louis that describe this event very well.

    Mike
    Therapeutic Drug Monitoring: Volume 22(3) June 2000 pp 320-322
    Lidocaine and Seizures


    DeToledo, John C.


    Department of Neurogy, University of Miami, Miami, Florida, USA
  3. by   lifeLONGstudent
    You can't fix dead. & "vomidate."

    Kevin,

    I like your choice of words: "you can't fix dead". :chuckle Pearls of wisdom to remember. Mind if I quote you?

    lifeLONGstudent

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