Yes, you can use a pressure infuser with IO devices. The drip rate can vary due to the anatomy of the space, but IO's are usually inserted during emergent situations. Placing it on a pressure bag will allow quick delivery of medication and fluid. After that, the doc can drop in a central line or IV team can place a stat PICC line once stabilized. We usually practice with a pressure bag in order to get everything in as fast as possible. Keeping it open to gravity takes too long and sometimes (although rare), gravity isn't enough to overcome the pressure in the IO space.