H5N1, Bird Flu Updates

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Tracking Bird Flu Cases

Bird flu deserves its own thread for tracking suspected and confirmed cases. It's not the pandemic virus, but it is still an ongoing and significant threat because of its virulence. As Margaret Chan, the Director General of the WHO says, we do not know how H5N1 will react under pressure from the pandemic virus, H1N1. All of the countries with endemic H5N1 are also reporting cases of swine flu. As everyone should know by now, the new concern revolves around what will happen if the two viruses co-infect the same host. Flu viruses exchange genetic material with each other all of the time. Right now we have a pandemic virus that is very transmissible, but does not kill the majority of people infected. Bird flu, on the other hand has a case fatality ratio (CFR) of around 60%.

In the past year, something different began to happen in Egypt. We started seeing many cases of young toddlers infected with mild cases of bird flu there. But, we also saw some older children and adults that had fatal cases. No one has yet explained why the disease began to change in Egypt. Just prior to the beginning of the swine flu cases appearing in the US and Mexico, the WHO was going to send in a team to Egypt to investigate why this was so. And, then the swine flu pandemic began in earnest, leaving this question unanswered. Why this situation has changed in Egypt but not in Indonesia, is most likely very important information.

Egypt continues to try to isolate swine flu cases. At some point, they won't be able to contain that virus, and will have to bow to the inevitable. Nobody knows what will happen then, but the Egyptians are clearly concerned. Remember, this is the country that slaughtered its entire pig population a few months ago to international dismay. Maybe they were right to do so, as we are now finding swine flu in pigs in Canada, Argentina and Australia. Pigs, the perfect mixing vessels for influenzas, may have been harboring the current swine flu for years undetected because they are almost never tested in most countries unless they are sick. This lack of disease surveillance is now being compensated for by a heightened awareness and increased testing of pig herds in many countries.

With all of that being said, here is a translation regarding a new case of bird flu, H5N1 in another child in Egypt. They do not state the child's age in this article, and some translations are saying that this is a male child. They would have isolated her anyway with bird flu, but with swine flu also in Egypt, they are likely to be very worried. Descriptions of these cases almost always mention dead birds being found in the same location. That of course, is going to be helpful in determing which flu they are dealing with at least for now, but maybe not later...

Egypt - Case #82

http://www.flutrackers.com/forum/showpost.php?p=272110&postcount=1

D. Abdel-Rahman Shahin, official spokesman of the Ministry of Health

The Ministry of Health on Sunday, a new human case of bird flu, a girl from a province of Kafr el-Sheikh for a total of 82 case of injuries so far.

A statement by the Ministry of Health said on Sunday that the new situation of the girl child is Muhammad Mustafa Ahmed Rania from the village of "Sidi Ghazi," the Department of Kafr El-Sheikh governorate of Kafr el-Sheikh.

The statement pointed out that the disease developed symptoms on July 24 of this hospital was incorporated in fevers of Kafr el-Sheikh on July 25 with a high temperature, running nose and cough after exposure to dead household birds, suspected of being infected with bird flu.

He also pointed out that the statement was given the drug "Tamiflu" as soon as the suspicion of being infected with the disease and her condition is stable and satisfactory communications are being carried out and procedures for the transfer to the hospital in the capital Cairo for the completion of treatment.

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Egyptian Bird Flu Case #93

Center Ghanyim Assiut Governorate

http://translate.google.com/translate?hl=en&ie=UTF-8&sl=ar&tl=en&u=http://www.youm7.com/News.asp%3FNewsID%3D180003%26SecID%3D65%26IssueID%3D87&prev=_t&rurl=translate.google.com

...the ministry announced the discovery of human case of bird flu, No. 93 for a child aged 3 years Center Ghanyim Assiut Governorate.

A statement of the "health" that the boy's parents reported being exposed to birds suspected of having bird flu, prompting authorities of the Ministry to take a sample for analysis after being suspected of becoming ill, but now, according to the statement, received the necessary treatment of his condition and became landed good.

(hat tip flutrackers/commonground)

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West Bengal, India

http://www.hindustantimes.com/india-news/westbengal/Bird-flu-back-in-W-Bengal/Article1-499909.aspx?

Bird flu has erupted in West Bengal after a gap of seven months.

Bhopal-based High Security Animal Disease Laboratory (HSADL) has found the bird flu virus (H5N1 strain) in seven out of 12 samples received from Murshidabad district, in the north-central part of the state.

"Three samples last week and four on Tuesday tested positive," HSADL Joint Director Shiv Charan Dubey told HT.

Based on the Bhopal lab report, the department of animal husbandry, dairy, and fisheries (DAHD) of the Centre has written to the West Bengal government, asking it to take steps like culling birds that are within 3 km of the Nagar and Hazarabati villages of the Khargram block, the centre of the outbreak. More than 3,000 birds had been culled in the area, sources said.

(hat tip pfi/pixie)

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http://afludiary.blogspot.com/2010/01/egyptian-media-reports-28th-h5n1.html

Sadly, the young woman in post #32 has died. They don't have her age exactly right but she is the 91st case of bird flu infection. Her death is not surprising. Why? Because most of the deaths from bird flu in Egypt have been in adult cases. The kids tend to survive. We don't know why. This strange anomaly has been occurring since last year. Right before the swine flu pandemic began, the WHO was supposed to be sending in a team to Egypt to investigate all of the new cases of bird flu because that was when the virus began infecting toddlers. It was a totally new demographic for bird flu in Egypt. And even more astounding, these kids were not dying like the adults. To this day, this has never been explained, and apparently this is still going on.

Ministry of Health announced the death of a No. 91 of avian flu, becoming the victim No. 28 of the disease since it appeared in Egypt in 2006 so far This is the first event of the death in 2010.

Case of a girl, aged "29 years" of Beni Suef, started showing symptoms on 6 January this year, and the effect was entered Beni Suef hospital on January 11, has been suffering from fever, cough, sore throat and difficulty in breathing, after exposure to dealing with dead birds suspected of being infected with the disease, and is beginning to emerge and given Tamiflu as of that date so far for more than 10 consecutive days, which confirms that the impact of the drug in the situation.

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Ha Tinh, Vietnam

http://crofsblogs.typepad.com/h5n1/2010/01/vietnam-bird-flu-recurs-in-ha-tinh---bird-flu-recurs-in-ha-tinh.html

They will never be able to eradicate H5N1 from Vietnam. This is like sticking a finger into a dyke.

A flock of ducks owned by Trinh Van Thuat in Tien Tien hamlet, Thach Quy ward, Ha Tinh province died en masse after being infected with bird flu virus, confirmed the Head of the provincial Veterinary Department, Pham Thanh Binh on January 21.

When almost all of this family's ducks died suddenly in 3 days from January 17-19, the provincial Veterinary Department took a test sample and the result showed positive for the H5N1 virus.

Quarantine stations have been set up in Thach Quy ward to monitor and control the transport of fowl from this locality.

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Karanganyar, Central Java, Indonesia

http://birdflucorner.wordpress.com/2010/01/27/karanganyar-central-java-patient-presumably-dies-of-bird-flu/

A resident of RT 03/ RW XVI Dukuh Josari Desa Wonorejo Jatiyoso, Wardi, 22 years old, presumably died of bird flu or avian influenza (AI) infection on Thursday (21/1).

Investigation of local newspaper Espos mentioned victim had high fever and lung infection. Head of Disease Control and Environment Health, Health Service of Kabupaten Karanganyar, Fatkhul Munir, confirmed the information above.

Fatkhul assumed victim had contracted bird flu virus in Cirebon. He had been sick when he returned back to Karanganyar, and finally died after had been admitted to hospital.

"Report mentioned victim had high fever and lung damage. Wardi also had contact history with birds," said Fatkhul.

(hat tip crofsblog)

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Kendrapara, India

http://www.expressbuzz.com/edition/story.aspx?Title=Bird+flu:+Sea+route+sealed&artid=AZEZk2NkCbY=

Bird flu: Sea route sealed

Express News ServiceFirst Published : 26 Jan 2010 04:54:00 AM IST

http://www.expressbuzz.com/edition/story.aspx?Title=Bird+flu:+Sea+route+sealed&artid=AZEZk2NkCbY=

KENDRAPARA: The Kendrapara district administration is on high alert after bird flu cases were reported in some parts of neighbouring West Bengal.

As an immediate action, sea routes in the district have been sealed to check the supply of poultry and chicks to the coastal pockets of the district, said District Collector Sishirkanta Panda.

''The officials of Mahakalapada and Rajnagar blocks have been directed to keep a close watch on the supply of poultry from West Bengal and the coast Guards and fishery officials too have been asked to prevent the supply of poultry through the sea routes to the coastal pockets'', added the Collector.

Around 23,000 poultry, including chicks, have been vaccinated within a month. ''The administration received 10,000 doses to vaccinate poultry'', said Dr G. Sar, CDVO of Kendrapara.

(hat tip pfi/pixie)

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Kibbutz Ein Shemer, Israel

http://www.israelnationalnews.com/News/Flash.aspx/179376?

An outbreak of bird flu was discovered Tuesday night at a henhouse in Kibbutz Ein Shemer. The disease was found in a henhouse containing about 43,000 hens. Agriculture Ministry workers began Tuesday night marking off the birds to be culled. All agricultural production in the area has been shut down until further notice.

(hat tip pfi/pixie)

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Indonesia

Ida at The Bird Flu Information Corner has a translation this morning of a new report on the 41 year-old agricultural extension worker from West Java (reported yesterday by Crof on Crofsblog) hospitalized and suspected of H5N1 infection. This comes on top of the report of a 10 year-old similarly hospitalized from East Java yesterday.

The problem is, whether positive or negative, we rarely hear how these cases turn out.

More at: http://afludiary.blogspot.com/2010/01/indonesian-beat-goes-on.html

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Bird Flu Back in Two Provinces of Vietnam

http://english.people.com.cn/90001/90777/90851/6879816.html?

The Vietnam's national committee on bird flu prevention and control said here on Tuesday that bird flu has reappeared in two provinces of Vietnam with nearly 4,000 poultry infected with the disease.

In the country's Mekong Delta province of Ca Mau, there have been 3,000 chickens, ducks and swans found infected with bird flu in two districts of the province.

In the central Ha Tinh province, about 658 chickens and ducks have acquired the H5N1 virus and become ill or died. All these poultry have not been injected with vaccines, according to the committee.

(hat tip crofsblog)

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Bangladesh

http://www.thedailystar.net/newDesign/latest_news.php?nid=21840

Are they really saying that H1N1 and H5N1 are in the same location and affecting birds?

Some 531 chickens were culled at a poultry farm in Gazipur on Monday in presence of the district livestock officer after it was affected by bird flu virus H5N1.

The district livestock authorities culled some 932 chickens and 183 eggs to contain the spread of the virus within 12 hours of confirmation.

Talking to The Daily Star, Jaypurhat District Livestock Officer Dr Shahidul Islam said the newly affected farm was less than half a kilometre away from the previous one where H1N1 virus was confirmed on January 5.

(hat tip crofsblog)

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While World Focused on Swine Flu, Bird Flu Kept Right on Trucking in 2009

For anyone unfamiliar with Scott McPherson's blog, he is the Chief Information Officer of the Florida House of Representatives. Scott is well connected to sources of information on H5N1 and other viruses. Scientists like to talk to him. I had the pleasure of meeting him personally when we both attended the last CIDRAP Conference in Minneapolis a few months ago. Dr. Osterholm of CIDRAP thinks highly enough of Scott's work that he invited him to be a presenter at that conference as a representative of the "new media" of bloggers focusing specifically on pandemic influenza. Scott is also one of the very nicest and smartest geeks that I have ever met. I am a big fan of his.

This recent commentary explains why there is still concern about H5N1 particularly with swine flu, H1N1 occurring in the same regions.

...the year 2009 shaped up as the fourth-worst year for human H5N1 cases on record, surpassed by (in order) 2006, 2005 and 2007 in terms of the sheer number of confirmed human cases. From 2008 to 2009, confirmed reported human bird flu cases jumped by 63% while deaths stabilized.

In 2010, we already are reading about more accounts of bird flu in poultry, in all the usual spots. This recent news, when combined with the 2009 data, should make us all more concerned than ever that a hybrid virus is more than just hypothetically possible. A glance at the WHO chart also shows us that the areas of the world where human H5N1 cases proliferate are also areas where the H1N1v virus is just beginning to make its inroads. China has recently announced it expects a constant flow of H1N1v human cases throughout 2010. China had 7 reported human bird flu cases in 2009, its third-highest year on record and the highest number since 2006.

Indeed, in those areas where H5N1 is assumed to be endemic, human cases are on par with previous years. For example, Egypt's 2009 human bird flu total (39) was 500% higher than 2008's (8). Vietnam's 5 cases was not statistically different than the previous two years. And in each and every one of those nations, H1N1v insinuates itself further and deeper rural villages and farms.

Read the full commentary at: http://www.scottmcpherson.net/journal/2010/1/26/while-world-focused-on-swine-flu-bird-flu-just-kept-on-truck.html

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fujian h5n1 in israel?

http://www.recombinomics.com/news/01271003/h5n1_israel_fujian.html?

i was wondering about that statement as well. how could they say that there was no danger to humans from h5n1 infected birds? who are they kidding? maybe they should ask the egyptians about this...

oth, i don't know if dr. niman is correct about the particular strain of h5n1. probably it doesn't matter. h5n1 is dangerous no matter what strain it is.

the health ministry said tuesday that the strain of bird flu discovered earlier would not infect humans.

the above comments from the israeli ministry of health raise concerns that the h5n1 outbreak reported to the oie is the fujian strain of h5n1 (clade 2.3.2).

the comments by the health ministry in israel were remarkably similar to comments from south korea when a soldier culler exhibited bird flu symptoms and was h5 positive. the fujian strain was responsible for most human h5n1 cases in china. however, at the time the human fujian cases had been clade 2.3.4. there was little reason to assume that clade 2.3.2 wouldn’t infect humans because human cases had been reported for clade 1 as well as clade 2.1, 2.2, and 2.3. therefore, it was likely that all sub-clades of 2.3 would be able to infect humans. in south korea the h5 virus was not isolated, so a formal report to who was not made and south korea remains free of human h5n1 cases. however, in early 2009 china did report a human infection involving clade 2.3.2. however, this distinction between 2.3.2 and 2.3.4 was not widely reported, so the israeli health ministry may still be assuming that the south koreans comments on human infections by clade 2.3.2 may still be accurate.

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