Sodium Modeling and UF profiling

Specialties Urology

Published

Hi,

Can someone explain Sodium modeling and UF profiling?

Thanks in advance

Specializes in Dialysis (acute & chronic).

Try looking at this link:

http://www.advancedrenaleducation.com/Hemodialysis/SodiumModeling/tabid/567/Default.aspx

Specializes in Dialysis.

They are tricks to attempt to remove more fluid. Sodium modeling involves setting the dialysate sodium to a level higher than the serum sodium and since water follows salt more water is removed. Usually it is set to the higher level for the first 2/3rds of the treatment to allow the serum sodium to return to a normal level during the last part of a treatment.

UF profiling involves pulling fluid off at different rates according to various pre set modes on the machine. Some profiles pull more at the beginning, some more at the end, the machines I am familiar with allow 8 different profiles. One of the problems with fluid removal in dialysis is that as fluid is removed from the blood it is replaced by fluid from the tissue and cells. If it is slower than the rate it is removed the blood pressure falls.

I think osmotic therapies, such as albumin or mannitol, are more effective but Na modeling and UF profiling give a few more options to the patient and the physician.

Specializes in Dialysis (acute & chronic).

Because of the high cost of albumin, you will not see this being used in chronic units. It is available to do acutes, since the hospital has to cover the cost.

100 ml of albumin about 15 years ago was $160 and 50 ml was $80.

Many clinics don't even have mannitol anymore, especially with bundling.

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