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Since I work in pediatrics, we give most of our medications via syringe pumps with small tubing. We use pre-filled syringes to flush our tubing after a medication is given because you only need a few mLs to flush and drawing from a bag is wasteful and less sterile. If we are giving a medication that is dispensed in a bag, then we flush with a bag of saline afterwards.
For routine flushing of our intravenous lines, we use pre-filled syringes, but we can draw up saline from a vial if needed.