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Valproic acid for pain?



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Sep 07, 2009 08:30 PM

Valproic acid for pain?


Has anybody heard of this? In looking around on the web I'm coming up goose eggs. I have to sign off on this to my cynical patients and I'M NOT convinced. Any help? Thanks Y'all.


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2 Comments
No. 1
from kids
Old Sep 07, 2009, 11:21 PM

Default Re: Valproic acid for pain?
Never heard of using it for pain.
I did find these:
Valproic Acid Not Effective for Polyneuropathic Pain
http://www.medscape.com/viewarticle/468519

Valproate for treatment of chronic central pain after spinal cord injury. A double-blind cross-over study.
http://www.ncbi.nlm.nih.gov/pubmed/7970862

http://www.cancer.org/docroot/CDG/co...proic_acid.asp

http://www.spineuniverse.com/display...ticle1614.html

http://books.google.com/books?id=lg7...20pain&f=false

And quite a bit of information on Valproate sodium for the treatment of migraines.
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No. 2
from Truegem
Old Sep 14, 2009, 01:25 AM

Default Re: Valproic acid for pain?
I found this:

"The valproic acid drugs are used as non-opioid pain relievers. They belong to a general class of drugs called anticonvulsants. These drugs may be given along with pain medicines to help control neuropathic pain of cancer (numbness, tingling, burning, shooting, or electric-shock-like pain.) They are also used for preventing seizures, preventing migraine headaches, and other purposes."
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