Valproic acid for pain?

Specialties Correctional

Published

Specializes in ER, HH, CTICU, corrections, cardiology, hospice.

Has anybody heard of this? In looking around on the web I'm coming up goose eggs. I have to sign off on this to my cynical patients and I'M NOT convinced. Any help? Thanks Y'all.

Never heard of using it for pain.

I did find these:

Valproic Acid Not Effective for Polyneuropathic Pain

http://www.medscape.com/viewarticle/468519

Valproate for treatment of chronic central pain after spinal cord injury. A double-blind cross-over study.

http://www.ncbi.nlm.nih.gov/pubmed/7970862

http://www.cancer.org/docroot/CDG/content/CDG_valproic_acid.asp

http://www.spineuniverse.com/displayarticle.php/article1614.html

http://books.google.com/books?id=lg7sIgP9D3kC&pg=PA185&lpg=PA185&dq=valproic+acid+%2B+pain&source=bl&ots=gd9BYuWw4v&sig=pTEu_S1AO0NxGdvRtxQH454Llzk&hl=en&ei=1dqlSs7hK4_wsQPIiYWNDw&sa=X&oi=book_result&ct=result&resnum=8#v=onepage&q=valproic%20acid%20%2B%20pain&f=false

And quite a bit of information on Valproate sodium for the treatment of migraines.

Specializes in Oncology, Corrections.

I found this:

"The valproic acid drugs are used as non-opioid pain relievers. They belong to a general class of drugs called anticonvulsants. These drugs may be given along with pain medicines to help control neuropathic pain of cancer (numbness, tingling, burning, shooting, or electric-shock-like pain.) They are also used for preventing seizures, preventing migraine headaches, and other purposes."

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