Ok-let me preface this by saying I am a first year SRNA. . . I have a question regarding potency of vecuronium. When doing a long case and you have used more than one bottle of vec has anyone had issues with what seemed to be different levels of potency between bottles?? I have had at least one case (maybe two) where pt would remain flat/or 1 twitch with same amount over same period of time-got a new bottle and just didn't seem to be working same way (no changes to any other settings-gas, etc. etc.) Mixed a new bottle and voila-was back in business. Just wondering if anyone else has experienced this- I looked online for any other discussions regarding this and couldn't find anything-maybe I am crazy, but the CRNA I was with suggested she had seen that before. Anyone????