Re: sedation protocol mechanically ventilated patient
As far as protocol, we dont have one. Sedation for mech vent pts should be on a case to case basis. If someone is unstable and being awake makes their stability more fluid, then by all means they need to be sedated. If the patient is having difficulty pulling their TV or has high PIPs or they are just "bucking the vent," so to speak, put them to sleep.
I prefer to use propofol. We arent allowed to bolus it, due to nursing practice in my state, but we can titrate it for therapuetic effect. It is best given centrally. On our propofol infusion orders we are allowed to titrate up to 50mcg/kg/min, and beyond that if the physician orders you to do so. I can tell you that they have no problem with this though. VORV to the rescue!!
Some physicians at my facility are opposed to propofol and prefer to use ativan or versed. I like propofol better because they wake up faster for t-piece trials than with the benzos. With these two we use standard bolus doses. We dont use versed drips. Ativan drips are dosed mg/hr, we usually start with a 2-4mg bolus then go from 1-10mg/hr on continuous infusion. Sometimes as high as 15mg. I hate ativan because in the experience I have had it crushes my pts pressure.
We also use a few paralytics. Pavulon, 0.1mg/kg bolus with repeat in 1-3 hrs. Zemeron 0.6-1.2mg/kg. Nimbex 1-1.7mcg/kg/min infusion. We used to use succs but have gone towards Nimbex more in the recent months. Succs is bad for those with high K, such as burns, crush injuries, and renal pts. Nimbex is also the paralytic of choice with increased HR, decreased MAP, bronchospams, or renal insufficiency/failure.
Unfortunately we are not using fentanyl any longer.
Anyone else have different experiences?
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