beta blocker function question

  1. 0
    Hi everyone,

    If beta agonists vasodilate, then why does a beta blocker ultimately lower blood pressure (I realize this is an unlabeled use, as they are more or less for reducing contractility in the heart)?

    Am I wrong in thinking that blocking vasodilation would actually elevate blood pressure?

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  2. 3 Comments...

  3. 0
    Quote from BlockIVstudent
    Hi everyone,

    If beta agonists vasodilate, then why does a beta blocker ultimately lower blood pressure (I realize this is an unlabeled use, as they are more or less for reducing contractility in the heart)?

    Am I wrong in thinking that blocking vasodilation would actually elevate blood pressure?
    First look up different receptor sites and where they are located (Alpha1, Alpha 2, Beta1, Beta 2). Once you have this information you should be able to figure out how they lower BP.

    You are correct in by block vasodilation you would increase BP.

    If you still don't understand after doing some research, come back with what you have learned and we can point you in the right direction.
  4. 0
    Antihypertensive action is not an off-label indication. It is right there on the package insert of most BB as FDA-approved indication for therapy.
  5. 0
    still a student, but i believe that the vasodilating property widens and relaxes the vessels, therefore the blood doesnt have to push as hard to get thru the arteries, which decreases the blood pressure...


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