Allergic Reactions Allergic Reactions | allnurses

LEGAL NOTICE TO THE FOLLOWING ALLNURSES SUBSCRIBERS: Pixie.RN, JustBeachyNurse, monkeyhq, duskyjewel, and LadyFree28. An Order has been issued by the United States District Court for the District of Minnesota that affects you in the case EAST COAST TEST PREP LLC v. ALLNURSES.COM, INC. Click here for more information

Allergic Reactions

  1. 0 Hi RNs,

    I know the standard of care for an allergic reaction in ER is Solumed, Benedryl, and Randine. I understand the Solumed and Benedryl, but what roles does the Randine play?

  2. 3 Comments

  3. Visit  meandragonbrett profile page
    #1 0
    Ranitidine is a Histamine2 antagonist.
  4. Visit  TDFlMedicRN profile page
    #2 1
    Quote from meandragonbrett
    Ranitidine is a Histamine2 antagonist.
    To elaborate somewhat; it is believed that H2 histamine blockers in conjunction with H1 blockers such as diphenhydramine have a synergistic effect; in other words, the two drugs potentiate each other when given together in the presence of a histamine reaction. This is an off-label use of an H2 antagonist, by the way.

    Additionally, H2 blockers can relieve the increased acid production which is a potential after effect of the catecholamine dump that will almost assuredly occur in a true histamine reaction.

  5. Visit  BlessedMomRN profile page
    #3 0
    thanks much!