Hi! I live and work in Alaska. I knew a couple that moved up from Ohio and they struggled with the transition. The major issues that motivated them to return to Ohio after 1 year is: not having family here, the much higher cost of living, and they were not very active in the winter. My advice to you would be to research housing. Look on craigslist at the housing in Anchorage, Eagle River. If you are adventurous and want to try the commute thing, housing is much cheaper in the Matsu Valley (Palmer and Wasilla). There is also a hospital in Palmer- Matsu Regional Medical Center. If you are looking for new grad programs, Providence Alaska Medical Center and Alaska Regional offer them. These hospitals still sometimes offer moving expenses or sign-on bonuses.